Article
Influence of hepatitis B virus X and core promoter mutations on hepatocellular carcinoma among patients infected with subgenotype C2.
Journal of clinical microbiology - 1 Oct 2007
Shinkai Noboru, Tanaka Yasuhito, Ito Kiyoaki, Mukaide Motokazu, Hasegawa Izumi, Asahina Yasuhiro, Izumi Namiki, Yatsuhashi Hiroshi, Orito Etsuro, Joh Takashi, Mizokami Masashi
Abstract excerpt
Hepatitis B virus (HBV) genotypes/subgenotypes and their related mutations in the HBV genome have been reported to be associated with hepatocellular carcinoma (HCC). To determine the HCC-associated mutations of the HBV genome in the entire X, core promoter, and precore/core regions, a cross-sectional control study was conducted comparing 80 Japanese patients infected with HBV C2 and suffering from HCC with 80...
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