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Comparison study on the complete sequence of hepatitis B virus identifies new mutations in core gene associated with hepatocellular carcinoma.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2010

Zhu Yu, Jin Yan, Guo Xia, Bai Xin, Chen Taoyang, Wang Jinbing, Qian Gengsun, Groopman John D, Gu Jianren, Li Jinjun, Tu Hong

Abstract excerpt

BACKGROUND: Mutations in the hepatitis B virus (HBV) genome may influence the activity of liver disease. The aim of this study was to identify new viral variations associated with hepatocellular carcinoma (HCC). METHODS: We carried out a comparison study on the complete sequence of HBV isolated from 20 HCC and 35 non-HCC patients in Qidong, China, an area with a high incidence of HCC. We compared the HBV...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 20699378
DOI: 10.1158/1055-9965.EPI-10-0469

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