Article
Potential Susceptibility Mutations in C Gene for Hepatitis B-Related Hepatocellular Carcinoma Identified by a Two-Stage Study in Qidong, China.
International journal of molecular sciences - 11 Oct 2016
Qu Lishuai, Zhang Haifeng, Liu Jinxia, Liu Taotao, Shen Xizhong, Chen Taoyang, Ni Zhengpin, Lu Cuihua
Abstract excerpt
A two stage study was conducted to explore new potential mutations in the full genome of hepatitis B virus (HBV) on the progression of hepatocellular carcinoma (HCC) in Qidong, China. In stage 1, full genomes of HBV were compared between 30 HCC cases and 30 controls. In stage 2, an independent case-control study including 100 HCC cases and 100 controls was enrolled to verify the relationship between hot-spot...
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