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Article

In vitro evolution of a fungal laccase in high concentrations of organic cosolvents.

Chemistry & biology - 1 Sept 2007

Zumárraga Miren, Bulter Thomas, Shleev Sergey, Polaina Julio, Martínez-Arias Arturo, Plou Francisco J, Ballesteros Antonio, Alcalde Miguel

Abstract excerpt

Fungal laccases are remarkable green catalysts that have a broad substrate specificity and many potential applications in bioremediation, lignocellulose processing, organic synthesis, and more. However, most of these transformations must be carried out at high concentrations of organic cosolvents in which laccases undergo unfolding, thereby losing their activity. We have tailored a thermostable laccase that...

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Identifiers

PMID: 17884637
DOI: 10.1016/j.chembiol.2007.08.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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