Article
Harnessing genetic diversity in Saccharomyces cerevisiae for fermentation of xylose in hydrolysates of alkaline hydrogen peroxide-pretreated biomass.
Applied and environmental microbiology - 1 Jan 2014
Sato Trey K, Liu Tongjun, Parreiras Lucas S, Williams Daniel L, Wohlbach Dana J, Bice Benjamin D, Ong Irene M, Breuer Rebecca J, Qin Li, Busalacchi Donald, Deshpande Shweta, Daum Chris, Gasch Audrey P, Hodge David B
Abstract excerpt
The fermentation of lignocellulose-derived sugars, particularly xylose, into ethanol by the yeast Saccharomyces cerevisiae is known to be inhibited by compounds produced during feedstock pretreatment. We devised a strategy that combined chemical profiling of pretreated feedstocks, high-throughput phenotyping of genetically diverse S. cerevisiae strains isolated from a range of ecological niches, and directed...
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