Article
Elevated expression and polymorphisms of SOCS3 influence patient response to antiviral therapy in chronic hepatitis C.
Gut - 1 Apr 2008
Persico M, Capasso M, Russo R, Persico E, Crocè L, Tiribelli C, Iolascon A
Abstract excerpt
BACKGROUND: The response to antiviral therapy of chronic hepatitis C virus (HCV) infection is determined by virological, environmental and genetic factors. OBJECTIVE: The hypothesis was tested that the expression of specific genes and their haplotype frequencies can differentiate between non-responders (NRs) and sustained virological responders (SVRs) to antiviral treatment. METHODS: A methodological approach...
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