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Article

SOCS3 genetic variants and promoter hypermethylation in patients with chronic hepatitis B.

Oncotarget - 7 Mar 2017

Hoan Nghiem Xuan, Van Tong Hoang, Giang Dao Phuong, Cuong Bui Khac, Toan Nguyen Linh, Wedemeyer Heiner, Bock C Thomas, Kremsner Peter G, Song Le Huu, Velavan Thirumalaisamy P

Abstract excerpt

The clinical manifestations of hepatitis B viral infection (HBV) include chronic hepatitis B (CHB), liver cirrhosis (LC) and hepatocellular carcinoma (HCC). The contribution of negative regulator suppressor of cytokine signaling-3 (SOCS3) promoter variants in HBV disease and SOCS3 hypermethylation in tumor tissues were investigated. The SOCS3 promoter region was screened for polymorphisms in 878 HBV patients and...

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Share to Carcinoma, Hepatocellular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 28179578
DOI: 10.18632/oncotarget.15083
PMCID: PMC5370028

Genes

SOCS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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