Article
Control of progression towards liver fibrosis and hepatocellular carcinoma by SOCS3 polymorphisms in chronic HCV-infected patients.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2018
Jadid Fatima Zahra, Chihab Hajar, Alj Hanane Salih, Elfihry Raouia, Zaidane Imane, Tazi Sanaa, Badre Wafaa, Marchio Agnes, El Filali Kamal Marhoum, Tahiri Mohammed, Saile Rachid, Pineau Pascal, Ezzikouri Sayeh, Benjelloun Soumaya
Abstract excerpt
BACKGROUND & AIMS: Chronic Hepatitis C is one of the most important risk factors of liver cirrhosis and hepatocellular carcinoma. Before reaching these ultimate steps, insulin resistance triggered by hepatitis C virus infection is known to participate in the progression of liver disease. The present study aims to investigate the influence of two functional polymorphisms on SOCS3 mRNA expression and on the...
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