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Article

Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants.

PloS one - 1 Jan 2012

Vidal Francesc, López-Dupla Miguel, Laguno Montserrat, Veloso Sergi, Mallolas Josep, Murillas Javier, Cifuentes Carmen, Gallart Lluis, Auguet Teresa, Sampériz Gloria, Payeras Antoni, Hernandez Pilar, Arnedo Mireia, Gatell Josep Ma, Richart Cristóbal

Abstract excerpt

BACKGROUND AND AIMS: This was a safety and efficacy pharmacogenetic study of a previously performed randomized trial which compared the effectiveness of treatment of hepatitis C virus infection with pegylated interferon alpha (pegIFNα) 2a vs. 2b, both with ribavirin, for 48 weeks, in HCV-HIV coin...

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Share to Gene Expression Regulation, Viral
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Suppressor of Cytokine Signaling 3 Protein

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Source

Open in PubMed Open full text

Identifiers

PMID: 23133602
DOI: 10.1371/journal.pone.0047725
PMCID: PMC3487790

Genes

SOCS3
CTLA4
ITPA
OAS1
CCL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23133602-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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