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Article

A polymorphism in MAPKAPK3 affects response to interferon therapy for chronic hepatitis C.

Gastroenterology - 1 May 2009

Tsukada Hironobu, Ochi Hidenori, Maekawa Toshiro, Abe Hiromi, Fujimoto Yoshifumi, Tsuge Masataka, Takahashi Hiroshi, Kumada Hiromitsu, Kamatani Naoyuki, Nakamura Yusuke, Chayama Kazuaki

Abstract excerpt

BACKGROUND & AIMS: This study aimed to identify host single nucleotide polymorphisms (SNPs) that are associated with the efficacy of interferon (IFN) therapy in patients with chronic hepatitis C. METHODS: We examined whether 116 tagging-SNPs from 13 genes that are involved in type I IFN signaling associate with the outcome of IFN therapy in Japanese case-control groups; the study included 468 sustained responders...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19208361
DOI: 10.1053/j.gastro.2009.01.061

Genes

MAPKAPK3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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