Article
Surfactant protein A activation of atypical protein kinase C zeta in IkappaB-alpha-dependent anti-inflammatory immune regulation.
Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2007
Moulakakis Christina, Adam Stefanie, Seitzer Ulrike, Schromm Andra B, Leitges Michael, Stamme Cordula
Abstract excerpt
The pulmonary collectin surfactant protein (SP)-A has a pivotal role in anti-inflammatory modulation of lung immunity. The mechanisms underlying SP-A-mediated inhibition of LPS-induced NF-kappaB activation in vivo and in vitro are only partially understood. We previously demonstrated that SP-A st...
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