Article
Surfactant protein A modulates the differentiation of murine bone marrow-derived dendritic cells.
American journal of physiology. Lung cellular and molecular physiology - 1 Jan 2003
Brinker Karen G, Garner Hollie, Wright Jo Rae
Abstract excerpt
Surfactant protein A (SP-A) is an innate immune molecule that regulates pathogen clearance and lung inflammation. SP-A modulates innate immune functions such as phagocytosis, cytokine production, and chemotaxis; however, little is known about regulation of adaptive immunity by SP-A. Dendritic cells (DCs) are the most potent antigen-presenting cell with the unique capacity to activate naive T cells and initiate...
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