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On the significance of Surfactant Protein-A within the human lungs

1 Jan 2009

Abstract excerpt

Surfactant Protein-A (SP-A) is the most prominent among four proteins in the pulmonary surfactant-system. SP-A is expressed by alveolar epithelial cells type II as well as by a portion of non small cell lung carcinomas (NSCLC).The expression of SP-A is complexly regulated on the transcriptional and the chromosomal level. SP-A is a major player in the pulmonary cytokine-network and moreover has been described to...

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PMID: 19284609
DOI: 10.1186/1746-1596-4-8

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