Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SURFACTANT PROTEIN A: AN INNATE IMMUNE MODULATOR AND THERAPEUTIC IN ASTHMA.

Transactions of the American Clinical and Climatological Association - 1 Jan 2024

Kraft Monica, Ledford Julie

Abstract excerpt

Surfactant Protein A (SP-A) is an innate immune modulator produced by the lung with known protective effects against bacteria and viruses. Its role in asthma, an inflammatory lung disease that affects 10% of the world's population, is not entirely known. In this review, we demonstrate that SP-A confers protection against exposure to interleukin-13, a type 2 cytokine integral to eosinophilic asthma, in a mouse...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anti-Asthmatic Agents
Share to Asthma
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunity, Innate

Share to Interleukin-13

Share to Pulmonary Surfactant-Associated Protein A

Share to Pyroglyphidae

Source

Open in PubMed Open full text

Identifiers

PMID: 39135597
PMCID: PMC11316857

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SURFACTANT PROTEIN A: AN INNATE IMMUNE MODULATOR AND THERAPEUTIC IN ASTHMA.PMID 39135597Read ↗

Immunomodulatory roles of surfactant proteins A and D: implications in lung disease.Semantic proximity Read ↗

Human Surfactant Protein SP-A1 and SP-A2 Variants Differentially Affect the Alveolar Microenvironment, Surfactant Structure, Regulation and Function of the Alveolar Macrophage, and Animal and Human Survival Under Various Conditions.Semantic proximity Read ↗

Genetic Complexity of the Human Innate Host Defense Molecules, Surfactant Protein A1 (SP-A1) and SP-A2Impact on FunctionSemantic proximity Read ↗

Genetic variant associations of human SP-A and SP-D with acute and chronic lung injury.Semantic proximity Read ↗

Air pollution and epigenetics: effects on SP-A and innate host defence in the lungSemantic proximity Read ↗

Differential effects of innate immune variants of surfactant protein-A1 (SFTPA1) and SP-A2 (SFTPA2) in airway function after Klebsiella pneumoniae infection and sex differences.Semantic proximity Read ↗

Surfactant protein D alters allergic lung responses in mice and human subjects.Semantic proximity Read ↗

Differential Immunoregulation by Human Surfactant Protein A Variants Determines Severity of SARS-CoV-2-induced Lung DiseaseSemantic proximity Read ↗

Surfactant protein A: A key player in lung homeostasisSemantic proximity Read ↗

Susceptibility of mice genetically deficient in the surfactant protein (SP)-A or SP-D gene to pulmonary hypersensitivity induced by antigens and allergens of Aspergillus fumigatus.Semantic proximity Read ↗

Relationship between surfactant protein A polymorphisms and allergic rhinitis in a Chinese Han population.Semantic proximity Read ↗

Differential Regulation of Human Surfactant Protein A Genes, SFTPA1 and SFTPA2, and Their Corresponding Variants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.