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Article

Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G.

FEBS letters - 2 Oct 2007

Chen Kuan-Ming, Martemyanova Natalia, Lu Yongjian, Shindo Keisuke, Matsuo Hiroshi, Harris Reuben S

Abstract excerpt

APOBEC3G is a single-strand DNA cytosine deaminase capable of blocking retrovirus and retrotransposon replication. APOBEC3G has two conserved zinc-coordinating motifs but only one is required for catalysis. Here, deletion analyses revealed that the minimal catalytic domain consists of residues 19...

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Share to Amino Acid Motifs
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytidine Deaminase

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Share to Protein Structure, Tertiary

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Source

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Identifiers

PMID: 17869248
DOI: 10.1016/j.febslet.2007.08.076
PMCID: PMC2014798

Genes

APOBEC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17869248-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Extensive mutagenesis experiments corroborate a structural model for the DNA deaminase domain of APOBEC3G.PMID 17869248Read ↗

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