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Article

The cytidine deaminase APOBEC3C has unique sequence and genome feature preferences.

Genetics - 7 Aug 2024

Brown Grant W

Abstract excerpt

APOBEC proteins are cytidine deaminases that restrict the replication of viruses and transposable elements. Several members of the APOBEC3 family, APOBEC3A, APOBEC3B, and APOBEC3H-I, can access the nucleus and cause what is thought to be indiscriminate deamination of the genome, resulting in mutagenesis and genome instability. Although APOBEC3C is also present in the nucleus, the full scope of its deamination...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38946641
DOI: 10.1093/genetics/iyae092
PMCID: PMC12117445

Genes

APOBEC3C
APOBEC3A
APOBEC3B
APOBEC3H

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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