Article
Association of IL23R, TNFRSF1A, and HLA-DRB1*0103 allele variants with inflammatory bowel disease phenotypes in the Finnish population.
Inflammatory bowel diseases - 1 Aug 2008
Lappalainen Maarit, Halme Leena, Turunen Ulla, Saavalainen Päivi, Einarsdottir Elisabet, Färkkilä Martti, Kontula Kimmo, Paavola-Sakki Paulina
Abstract excerpt
BACKGROUND: Crohn's disease (CD) and ulcerative colitis (UC), 2 major forms of inflammatory bowel disease (IBD), are complex disorders with significant genetic predisposition. The first CD-associated gene, CARD15/NOD2, was recently identified and since then several reports on novel IBD candidate genes have emerged. We investigated disease phenotype association to genetic variations in IL23R, ATG16L1, DLG5,...
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