Article
IL23R and IL12B polymorphisms in Spanish IBD patients: no evidence of interaction.
Inflammatory bowel diseases - 1 Sept 2008
Márquez Ana, Mendoza Juan Luis, Taxonera Carlos, Díaz-Rubio Manuel, De La Concha Emilio G, Urcelay Elena, Martínez Alfonso
Abstract excerpt
BACKGROUND: Recent genomic surveys have identified IL23R and IL12B as susceptibility loci for inflammatory bowel disease (IBD). Our aim in the present study was to ascertain whether the IL23R and IL12B associations with IBD are also observed in our population, and to analyze possible genetic interactions between polymorphisms at IL12B and IL23R, ligand and receptor, respectively. METHODS: In all, 707 IBD patients...
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