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Article

Deletion of a small consensus region at 6q15, including the MAP3K7 gene, is significantly associated with high-grade prostate cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Sept 2007

Liu Wennuan, Chang Bao-Li, Cramer Scott, Koty Patrick P, Li Tao, Sun Jishan, Turner Aubrey R, Von Kap-Herr Chris, Bobby Peggy, Rao Jianyu, Zheng S Lilly, Isaacs William B, Xu Jianfeng

Abstract excerpt

PURPOSE: Chromosome 6q14-21 is commonly deleted in prostate cancers, occurring in approximately 22% of all tumors and approximately 40% of metastatic tumors. However, candidate prostate tumor suppressor genes in this region have not been identified, in part due to the large and broad nature of the deleted region implicated in previous studies. EXPERIMENTAL DESIGN: We first used high-resolution Affymetrix single...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17785553
DOI: 10.1158/1078-0432.CCR-07-0300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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