Article
Association of a novel long non-coding RNA in 8q24 with prostate cancer susceptibility.
Cancer science - 1 Jan 2011
Chung Suyoun, Nakagawa Hidewaki, Uemura Motohide, Piao Lianhua, Ashikawa Kyota, Hosono Naoya, Takata Ryo, Akamatsu Shusuke, Kawaguchi Takahisa, Morizono Takashi, Tsunoda Tatsuhiko, Daigo Yataro, Matsuda Koichi, Kamatani Naoyuki, Nakamura Yusuke, Kubo Michiaki
Abstract excerpt
Recent genome-wide association studies reported strong and reproducible associations of multiple genetic variants in a large "gene-desert" region of chromosome 8q24 with susceptibility to prostate cancer (PC). However, the causative or functional variants of these 8q24 loci and their biological mechanisms associated with PC susceptibility remain unclear and should be investigated. Here, focusing on its most...
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