Article
Genome-wide copy number analysis reveals candidate gene loci that confer susceptibility to high-grade prostate cancer.
Urologic oncology - 1 Sept 2017
Poniah Prevathe, Mohd Zain Shamsul, Abdul Razack Azad Hassan, Kuppusamy Shanggar, Karuppayah Shankar, Sian Eng Hooi, Mohamed Zahurin
Abstract excerpt
BACKGROUND: Two key issues in prostate cancer (PCa) that demand attention currently are the need for a more precise and minimally invasive screening test owing to the inaccuracy of prostate-specific antigen and differential diagnosis to distinguish advanced vs. indolent cancers. This continues to pose a tremendous challenge in diagnosis and prognosis of PCa and could potentially lead to overdiagnosis and...
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