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Article

Genome-wide detection of LOH in prostate cancer using human SNP microarray technology.

Genomics - 1 Mar 2003

Dumur Catherine I, Dechsukhum Chavaboon, Ware Joy L, Cofield Stacey S, Best Al M, Wilkinson David S, Garrett Carleton T, Ferreira-Gonzalez Andrea

Abstract excerpt

Loss of heterozygosity (LOH) of chromosomal regions is crucial in tumor progression. In this study we assessed the potential of the Affymetrix GeneChip HuSNP mapping assay for detecting genome-wide LOH in prostate tumors. We analyzed two human prostate cell lines, P69SV40Tag (P69) and its tumorigenic subline, M12, and 11 prostate cancer cases. The M12 cells showed LOH in chromosomes 3p12.1-p22.1, 11q22.1-q24.2,...

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Identifiers

PMID: 12659810
DOI: 10.1016/s0888-7543(03)00020-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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