Article
An 800-kb region of deletion at 13q14 in human prostate and other carcinomas.
Genomics - 1 Oct 2001
Chen C, Frierson H F, Haggerty P F, Theodorescu D, Gregory C W, Dong J T
Abstract excerpt
Deletions of regions at 13q14 have been detected by various genetic approaches in human cancers including prostate cancer. Several studies have defined one region of loss of heterozygosity (LOH) at 13q14 that seems to reside in a DNA segment of 7.1 cM between genetic markers D13S263 and D13S153. To define the smallest region of overlap (SRO) for deletion at 13q14, we first applied tissue microdissection and...
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