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Article

Homozygous deletions and recurrent amplifications implicate new genes involved in prostate cancer.

Neoplasia (New York, N.Y.) - 1 Aug 2008

Liu Wennuan, Xie Chunmei Carol, Zhu Yi, Li Tao, Sun Jishan, Cheng Yu, Ewing Charles M, Dalrymple Sue, Turner Aubrey R, Sun Jielin, Isaacs John T, Chang Bao-Li, Zheng Siqun Lilly, Isaacs William B, Xu Jianfeng

Abstract excerpt

Prostate cancer cell lines provide ideal in vitro systems for the identification and analysis of prostate tumor suppressors and oncogenes. A detailed characterization of the architecture of prostate cancer cell line genomes would facilitate the study of precise roles of various genes in prostate tumorigenesis in general. To contribute to such a characterization, we used the GeneChip 500K single nucleotide...

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Share to Chromosomes, Human, Pair 8
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Amplification

Share to In Situ Hybridization, Fluorescence

Share to Loss of Heterozygosity

Share to Prostatic Neoplasms

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Source

Open in PubMed Open full text

Identifiers

PMID: 18670647
DOI: 10.1593/neo.08428
PMCID: PMC2481576

Genes

MYC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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