Article
UTF1 is a chromatin-associated protein involved in ES cell differentiation.
The Journal of cell biology - 10 Sept 2007
van den Boom Vincent, Kooistra Susanne M, Boesjes Marije, Geverts Bart, Houtsmuller Adriaan B, Monzen Koshiro, Komuro Issei, Essers Jeroen, Drenth-Diephuis Loes J, Eggen Bart J L
Abstract excerpt
Embryonic stem (ES) cells are able to grow indefinitely (self-renewal) and have the potential to differentiate into all adult cell types (pluripotency). The regulatory network that controls pluripotency is well characterized, whereas the molecular basis for the transition from self-renewal to the differentiation of ES cells is much less understood, although dynamic epigenetic gene silencing and chromatin...
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