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Article

Quantitative measurement of postural sway in mouse models of human neurodegenerative disease.

Neuroscience - 21 Sept 2007

Hutchinson D, Ho V, Dodd M, Dawson H N, Zumwalt A C, Schmitt D, Colton C A

Abstract excerpt

Detection of motor dysfunction in genetic mouse models of neurodegenerative disease requires reproducible, standardized and sensitive behavioral assays. We have utilized a center of pressure (CoP) assay in mice to quantify postural sway produced by genetic mutations that affect motor control centers of the brain. As a positive control for postural instability, wild type mice were injected with harmaline, a...

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Identifiers

PMID: 17764851
DOI: 10.1016/j.neuroscience.2007.07.025
PMCID: PMC2175386

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NOS2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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