Article
Longitudinal evaluation of an N-ethyl-N-nitrosourea-created murine model with normal pressure hydrocephalus.
PloS one - 17 Nov 2009
Lee Ming-Jen, Chang Ching-Pang, Lee Yi-Hsin, Wu Yi-Chih, Tseng Hsu-Wen, Tung Yu-Ying, Wu Min-Tzu, Chen Yen-Hui, Kuo Lu-Ting, Stephenson Dennis, Hung Shuen-Iu, Wu Jer-Yuarn, Chang Chen, Chen Yuan-Tsong, Chern Yijuang
Abstract excerpt
BACKGROUND: Normal-pressure hydrocephalus (NPH) is a neurodegenerative disorder that usually occurs late in adult life. Clinically, the cardinal features include gait disturbances, urinary incontinence, and cognitive decline. METHODOLOGY/PRINCIPAL FINDINGS: Herein we report the characterization o...
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