Article

Integrated Gait and Pose Analysis Utilizing Computer Vision for Parkinsonian Behavioral Phenotyping in Mice

2026-03-11

Abstract excerpt

Synucleinopathies can be biologically advanced before overt parkinsonism is clinically apparent, highlighting the need for objective, sensitive motor endpoints. We examined the mThy1-α-synuclein line 61 (L61-Tg) mouse, which shows progressive synucleinopathy with early circuit dysfunction, using an integrated pipeline combining CatWalk XT gait analysis and markerless pose estimation from the same CatWalk videos. T...

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Literature Corpus work: 00b4416f-ea7e-592f-8b51-26d41d3283f8
DOI: 10.64898/2026.03.10.706230

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