Article
Cis sequence effects on gene expression.
BMC genomics - 29 Aug 2007
Bergen Andrew W, Baccarelli Andrea, McDaniel Timothy K, Kuhn Kenneth, Pfeiffer Ruth, Kakol Jerry, Bender Patrick, Jacobs Kevin, Packer Bernice, Chanock Stephen J, Yeager Meredith
Abstract excerpt
BACKGROUND: Sequence and transcriptional variability within and between individuals are typically studied independently. The joint analysis of sequence and gene expression variation (genetical genomics) provides insight into the role of linked sequence variation in the regulation of gene expression. We investigated the role of sequence variation in cis on gene expression (cis sequence effects) in a group of genes...
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