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Article

Cis and trans effects of human genomic variants on gene expression.

PLoS genetics - 1 Jul 2014

Bryois Julien, Buil Alfonso, Evans David M, Kemp John P, Montgomery Stephen B, Conrad Donald F, Ho Karen M, Ring Susan, Hurles Matthew, Deloukas Panos, Davey Smith George, Dermitzakis Emmanouil T

Abstract excerpt

Gene expression is a heritable cellular phenotype that defines the function of a cell and can lead to diseases in case of misregulation. In order to detect genetic variations affecting gene expression, we performed association analysis of single nucleotide polymorphisms (SNPs) and copy number variants (CNVs) with gene expression measured in 869 lymphoblastoid cell lines of the Avon Longitudinal Study of Parents...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25010687
DOI: 10.1371/journal.pgen.1004461
PMCID: PMC4091791

Genes

BATF3
HMX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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