Article
Abundant raw material for cis-regulatory evolution in humans.
Molecular biology and evolution - 1 Nov 2002
Rockman Matthew V, Wray Gregory A
Abstract excerpt
Changes in gene expression and regulation--due in particular to the evolution of cis-regulatory DNA sequences--may underlie many evolutionary changes in phenotypes, yet little is known about the distribution of such variation in populations. We present in this study the first survey of experimentally validated functional cis-regulatory polymorphism. These data are derived from more than 140 polymorphisms involved...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
