Article
Population genomics of human gene expression.
Nature genetics - 1 Oct 2007
Stranger Barbara E, Nica Alexandra C, Forrest Matthew S, Dimas Antigone, Bird Christine P, Beazley Claude, Ingle Catherine E, Dunning Mark, Flicek Paul, Koller Daphne, Montgomery Stephen, Tavaré Simon, Deloukas Panos, Dermitzakis Emmanouil T
Abstract excerpt
Genetic variation influences gene expression, and this variation in gene expression can be efficiently mapped to specific genomic regions and variants. Here we have used gene expression profiling of Epstein-Barr virus-transformed lymphoblastoid cell lines of all 270 individuals genotyped in the HapMap Consortium to elucidate the detailed features of genetic variation underlying gene expression variation. We find...
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