Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

[The optimal treatment of chronic heart failure with beta-blockers may be dependent upon the genetic background of the patient].

Nederlands tijdschrift voor geneeskunde - 21 Jul 2007

Leschot N J, Wilde A A M

Abstract excerpt

Pharmacogenetics, which aims at the development of'personal pills', is an attractive field in modern medicine. However, the results obtained in the last few years are somewhat disappointing. Recently, a genetic polymorphism was discovered in the treatment of chronic heart failure with beta-blockers. An in-vitro study revealed a hypersensitivity of the Arg389 variant in the beta1-adrenergic receptor to the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenergic beta-Antagonists
Share to Carbazoles
Share to Genomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heart Failure

Share to Pharmacogenetics

Share to Polymorphism, Genetic

Share to Propanolamines

Share to Treatment Outcome

Source

Identifiers

PMID: 17727180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

[The optimal treatment of chronic heart failure with beta-blockers may be dependent upon the genetic background of the patient].PMID 17727180Read ↗

[Adrenergic receptor polymorphisms in heart failure: what can genetics explain?].Semantic proximity Read ↗

[The clinical pharmacology of beta-adrenoblockers].Semantic proximity Read ↗

β-adrenergic receptor polymorphisms in susceptibility, response to treatment and prognosis in heart failure: implication of ethnicity.Semantic proximity Read ↗

State of play of pharmacogenetics and personalized medicine in heart failure.Semantic proximity Read ↗

[Pharmacogenetics of chronic heart failure--beta blockers].Semantic proximity Read ↗

[Impact of Gly389Arg beta1-adrenoceptor polymorphism on the risk of chronic heart failure, the nature of its course, and on the efficiency of its treatment with carvedilol].Semantic proximity Read ↗

Impact of the β1-adrenoceptor Arg389Gly polymorphism on heart-rate responses to bisoprolol and carvedilol in heart-failure patients.Semantic proximity Read ↗

Pharmacogenetic polymorphisms affecting bisoprolol response.Semantic proximity Read ↗

Impact of the β-1 adrenergic receptor polymorphism on tolerability and efficacy of bisoprolol therapy in Korean heart failure patients: association between β adrenergic receptor polymorphism and bisoprolol therapy in heart failure (ABBA) study.Semantic proximity Read ↗

β1 adrenergic receptor polymorphisms and heart failure: a meta-analysis on susceptibility, response to β-blocker therapy and prognosis.Semantic proximity Read ↗

Gly389Arg polymorphism of beta1-adrenergic receptor is associated with the cardiovascular response to metoprolol.Semantic proximity Read ↗

Impact of beta1-adrenergic receptor polymorphisms on susceptibility to heart failure, arrhythmogenesis, prognosis, and response to beta-blocker therapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.