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Article

Impact of beta1-adrenergic receptor polymorphisms on susceptibility to heart failure, arrhythmogenesis, prognosis, and response to beta-blocker therapy.

The American journal of cardiology - 15 Sept 2008

Biolo Andréia, Clausell Nadine, Santos Kátia G, Salvaro Roberto, Ashton-Prolla Patrícia, Borges Anibal, Rohde Luis E

Abstract excerpt

Beta1-adrenergic receptor polymorphisms have been implicated with inconsistent results in the pathogenesis, clinical presentation, and prognosis of patients with heart failure (HF). The impact of 2 functional polymorphisms (beta1-Arg389Gly and beta1-Ser49Gly) on HF susceptibility, arrhythmogenesis, and prognosis was evaluated in Brazilian outpatients. Genotyping at codons 389 and 49 was performed using polymerase...

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Share to Adrenergic beta-Antagonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Dose-Response Relationship, Drug

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Share to Receptors, Adrenergic, beta-1

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Share to Tachycardia, Ventricular

Source

Identifiers

PMID: 18773997
DOI: 10.1016/j.amjcard.2008.04.070

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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