[The clinical pharmacology of beta-adrenoblockers].

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Article

[The clinical pharmacology of beta-adrenoblockers].

Klinicheskaia meditsina - 1 Jan 2006

Sychev D A, Ramenskaia G V, Ignat'ev I V, Smirnikhina S A, Kazakov R E, Kukes V G

Abstract excerpt

Beta-adrenoblockers (BAB) are highly-effective pharmaceuticals used broadly in treatment of cardial diseases. Response to BABs is known to display interindividual variability; pre-treatment analysis of allelic gene variants responsible for BAB pharmacokinetics, allows dose correction according to the genetic features of an individual patient. Pharmacogenetics is a young science, but it has already proven its...

Topics

Adrenergic beta-Antagonists
Cytochrome P-450 CYP2D6
DNA
Genotype
Heart Diseases
Humans
Pharmacogenetics
Polymorphism, Genetic

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PMID: 16758913

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