Article
[Impact of Gly389Arg beta1-adrenoceptor polymorphism on the risk of chronic heart failure, the nature of its course, and on the efficiency of its treatment with carvedilol].
Terapevticheskii arkhiv - 1 Jan 2010
Tepliakov A T, Shilov S N, Berezikova E N, Torim Iu Iu, Efremov A V, Safronov I D, Maianskaia S D, Popova A A, Voronina E N, Karpov R S
Abstract excerpt
AIM: To study beta1-adrenoceptor gene (ADRB1) polymorphism on the development and course of chronic heart failure (CHF) and on the efficiency of its treatment with the beta-adrenoblocker carvedilol in patients with coronary heart failure. SUBJECTS AND METHODS: Two hundred and twenty-six patients (149 males and 77 females; mean age 55.9 +/- 5.8 years) with CHF, who received continuous basic therapy:...
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