Article
State of play of pharmacogenetics and personalized medicine in heart failure.
Cardiovascular therapeutics - 1 Dec 2013
Parry Helen M, Doney Alex S F, Palmer Colin N A, Lang Chim C
Abstract excerpt
Heart failure is a common disease with high levels of morbidity and mortality. A large body of evidence guiding treatment shows prognostic benefit with beta-blockers and angiotensin-converting enzyme inhibitors, while diuretics are commonly prescribed for symptomatic benefit. Wide variation in drug response between clinically similar patients is a significant problem. Evidence suggests this may have a genetic...
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