Article
[Adrenergic receptor polymorphisms in heart failure: what can genetics explain?].
Arquivos brasileiros de cardiologia - 1 Jun 2010
Pereira Sabrina Bernardez, Gava Isabela Ambrósio, Giro Camila, Mesquita Evandro Tinoco
Abstract excerpt
Heart failure (HF) is a complex disease, which involves several physiopathological mechanisms and different genetic polymorphisms. The adrenergic system is directly related to this pathology, as it participates in cardiovascular autoregulation and has a crucial role in the deterioration of cardiac function. The beta-blockers appeared as a great advance in cardiology for the treatment of HF; however, the drug...
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