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Article

Proteome analysis of chemically induced mouse liver tumors with different genotype.

Proteomics - 1 Sept 2007

Strathmann Julia, Paal Krisztina, Ittrich Carina, Krause Eberhard, Appel Klaus E, Glauert Howard P, Buchmann Albrecht, Schwarz Michael

Abstract excerpt

Mouse liver tumors frequently harbor mutations in Ha-ras, B-raf, or Ctnnb1 (encoding beta-catenin). We conducted a proteome analysis with protein extracts from normal mouse liver and from liver tumors which were induced by a single injection of N-nitrosodiethylamine (DEN) as initiator followed by multiple injections of two different polychlorinated biphenyls (PCBs) as tumor promoters, or corn oil as a control....

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Identifiers

PMID: 17722141
DOI: 10.1002/pmic.200600983

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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