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Article

Molecular profiling of hepatocellular carcinoma in mice with a chronic deficiency of hepatic s-adenosylmethionine: relevance in human liver diseases.

Journal of proteome research - 1 Apr 2006

Santamaría Enrique, Muñoz Javier, Fernandez-Irigoyen Joaquín, Sesma Laura, Mora María I, Berasain Carmen, Lu Shelly C, Mato José M, Prieto Jesús, Avila Matías A, Corrales Fernando J

Abstract excerpt

S-adenosylmethionine arises as a central molecule in the preservation of liver homeostasis as a chronic hepatic deficiency results in spontaneous development of steatohepatitis and hepatocellular carcinoma. In the present work, we have attempted a comprehensive analysis of proteins associated with hepatocarcinogenesis in MAT1A knock out mice using a combination of two-dimensional electrophoresis and mass...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16602702
DOI: 10.1021/pr050429v

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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