Back to search

Article

Differential Proteomic Analysis of DEN-Induced Hepatocellular Carcinoma in Male and Female Balb/c Mice Reveals Novel Gender Specific Markers

2025-05-19

Abstract excerpt

<h4>Background</h4> Hepatocellular carcinoma (HCC) is one of the leading causes of hepatic malignancy with a higher prevalence in males compared to females, however, the distinct underlying mechanisms contributing to this disparity remain poorly understood. <h4>Methods</h4> In this study, we aimed to investigate comparative proteome profiling of a diethylnitrosamine (DEN) induced HCC model in male and female Bal...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
d6ca2a9d-45c0-541f-8362-ea5237f6ed80
DOI
10.1101/2025.05.15.654000
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Differential Proteomic Analysis of DEN-Induced Hepatocellular Carcinoma in Male and Female Balb/c Mice Reveals Novel Gender Specific MarkersDOI 10.1101/2025.05.15.654000
A new chemical carcinogen and Western diet protocol to reliably induce advanced hepatocellular carcinoma in male and female miceSemantic proximity
Identification and characterization of sexual dimorphism‑linked gene expression profile in hepatocellular carcinomaSemantic proximity
Proteome analysis of chemically induced mouse liver tumors with different genotype.Semantic proximity
Sex differences in bile acid homeostasis and excretion underlie the disparity in liver cancer incidence between males and femalesSemantic proximity
Comparative hepatic proteome analysis between lean and obese rats fed a high-fat diet reveals the existence of gender differences.Semantic proximity
Sex-specific differences in preclinical models of advanced chronic liver disease and portal hypertensionSemantic proximity
Lipidomic Analysis on Gender-Dependent Hepatocellular Carcinogenesis in Hras12V Transgenic MiceSemantic proximity
Unraveling the Molecular Links between Benzopyrene Exposure, NASH, and HCC: An Integrated Bioinformatics and Experimental StudySemantic proximity
The Time-Course of Cancer Cachexia Onset Reveals Biphasic Transcriptional Disruptions in Female Skeletal Muscle Distinct from MalesSemantic proximity
Sex-dependent pathways in hepatocarcinogenesis triggered by deregulated cholesterol synthesisSemantic proximity
Gene expression, regulation of DEN and HBx induced HCC mice models and comparisons of tumor, para-tumor and normal tissuesSemantic proximity
Integrative genomic analysis of mouse and human hepatocellular carcinomaSemantic proximity
Select a neighboring publication to make it the new centre.