Article
The Applicability of a Human Immunohistochemical Panel to Mouse Models of Hepatocellular Neoplasia.
Comparative medicine - 1 Oct 2015
Salleng Kenneth J, Revetta Frank L, Deane Natasha G, Washington M Kay
Abstract excerpt
Various immunohistochemical panels are used as aids to distinguish between primary hepatocellular malignancies and metastatic tumors and between benign lesions and carcinomas. We compared the immunohistochemical spectrum of hepatocellular lesions in mice with that of human hepatocellular carcinoma (HCC). Specifically, we compared the staining parameters of 128 murine foci of cellular alteration (FCA) and tumors...
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