Article
The elongation factor Elof1 is required for mammalian gastrulation.
PloS one - 1 Jan 2019
Tellier Adam P, Archambault Danielle, Tremblay Kimberly D, Mager Jesse
Abstract excerpt
Despite having been sequenced over a decade ago, the functional significance of much of the mammalian genome remains unknown. The mouse has become the preeminent mammalian model for identifying endogenous gene function in vivo. Here we characterize the phenotype of a loss-of function allele for the evolutionarily conserved transcription factor, Elongation Factor Homolog 1 (Elof1). Recent work utilizing the yeast...
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