Article
The PAF1 complex is involved in embryonic epidermal morphogenesis in Caenorhabditis elegans.
Developmental biology - 1 Jul 2014
Kubota Yukihiko, Tsuyama Kenji, Takabayashi Yusuke, Haruta Nami, Maruyama Rika, Iida Naoko, Sugimoto Asako
Abstract excerpt
The PAF1 complex (PAF1C) is an evolutionarily conserved protein complex involved in transcriptional regulation and chromatin remodeling. How the PAF1C is involved in animal development is still not well understood. Here, we report that, in the nematode Caenorhabditis elegans, the PAF1C is involved in epidermal morphogenesis in late embryogenesis. From an RNAi screen we identified the C. elegans ortholog of a...
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