Article
dELL is an essential RNA polymerase II elongation factor with a general role in development.
Proceedings of the National Academy of Sciences of the United States of America - 23 Jul 2002
Eissenberg Joel C, Ma Jiyan, Gerber Mark A, Christensen Alan, Kennison James A, Shilatifard Ali
Abstract excerpt
Several eukaryotic proteins increase RNA polymerase II (Pol II) transcription rates in vitro. The relative contributions of these factors to gene expression in vivo is unknown. The ELL family of proteins promote Pol II elongation in vitro, and the Drosophila ELL homolog (dELL) is associated with Pol II at sites of transcription in vivo. The purpose of this study was to test whether an ELL family protein is...
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