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Article

RNA polymerase II subunit D is essential for zebrafish development.

Scientific reports - 6 Aug 2020

Maeta Masanari, Kataoka Miku, Nishiya Yusuke, Ogino Kazutoyo, Kashima Makoto, Hirata Hiromi

Abstract excerpt

DNA-directed RNA polymerase II (pol II) is composed of ten core and two dissociable subunits. The dissociable subcomplex is a heterodimer of Rpb4/Polr2d and Rpb7/Polr2g, which are encoded by RPB4/polr2d and RPB7/polr2g genes, respectively. Functional studies of Rpb4/Polr2d in yeast have revealed that Rpb4 plays a role primarily in pol II-mediated RNA synthesis and partly in various mRNA regulations including...

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Identifiers

PMID: 32764610
DOI: 10.1038/s41598-020-70110-1
PMCID: PMC7413394

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