Article
Involvement of p53 R72P polymorphism in the association of MDM2-SNP309 with breast cancer.
Oncology reports - 1 Jun 2011
Leu Jyh-Der, Wang Chung-Yih, Tsai Han-Yi, Lin I-Feng, Chen Ran-Chou, Lee Yi-Jang
Abstract excerpt
The allelic variant MDM2-SNP309 (T>G) has been suggested to influence cancer development, but the clinical correlation between the risk allele and breast cancer remains controversial. The genetic background and the ethnicity of selected subgroups may influence the power of these risk genotypes. In this study, we investigated whether MDM2-SNP309 is associated with p53 R72P genetic polymorphism for the risk of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
