Article
Oestrogen receptors and linear bone growth.
Acta paediatrica (Oslo, Norway : 1992) - 1 Sept 2007
Chagin Andrei S, Sävendahl Lars
Abstract excerpt
In this review we summarize available data regarding linear growth in oestrogen receptor alpha (ERalpha)- and oestrogen receptor beta (ERbeta)-deficient mice. We discuss these findings in relation to known oestrogenic effects in humans and the possibility of applying this knowledge for the therapeutic modulation of longitudinal bone growth employing selective oestrogen receptor modulators (SERMs). We conclude...
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