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Article

Estrogen receptor alpha mediates mandibular condylar cartilage growth in male mice.

Orthodontics & craniofacial research - 1 Jun 2017

Robinson J L, Gupta V, Soria P, Clanaman E, Gurbarg S, Xu M, Chen J, Wadhwa S

Abstract excerpt

OBJECTIVES: In the appendicular skeleton, estrogen via ERα signalling has been shown to mediate endochondral growth plate fusion in both males and females. However, the role of ERα in mediating growth of the mandibular condylar cartilage is unknown. Thus, this study focuses on the characterization of the mandibular condylar cartilage phenotype in young and adult male ERαKO mice. SETTING: Columbia University...

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Share to Cartilage, Articular
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28643917
DOI: 10.1111/ocr.12155
PMCID: PMC5562277

Genes

DMP1
MCC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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