Article
Effects of sex steroid receptor specificity in the regulation of skeletal metabolism.
Calcified tissue international - 1 Jul 2004
Tözüm T F, Oppenlander M E, Koh-Paige A J, Robins D M, McCauley L K
Abstract excerpt
The interaction between estrogens and androgens, with their protective effects in bone, and parathyroid hormone (PTH), a calcitropic peptide hormone, is complex but may be better understood with murine models. The purpose of this study was to characterize skeletal phenotypes of mice deficient in estrogen receptor alpha (ERalpha), androgen receptor (AR, mutant tfm), or both, and determine if ERalpha and AR alter...
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